Low Dose Naltrexone

Intermittent Opiate Antagonist

At a Glance

  • Innovative treatment option for autoimmune and inflammation
  • Aids in the regulation of immune system activity
  • Administered orally once daily
  • Two different strength Immediate Release capsules (1.5mg & 4.5mg)

The Details

Low-Dose Naltrexone (LDN) is known as an effective treatment for conditions such as autoimmune diseases, inflammation, and certain types of pain. This innovative solution works by modulating the immune system, offering a simple, daily oral dose to manage various symptoms. With multiple strengths of LDN capsules available, this allows individuals more dosing options based on the disease states and symptoms the patient is experiencing.

Prescription Required
menMD does not compound or dispense prescription products. Prescriptions are filled through our US-licensed pharmacy partners.

Starting at $1.09 per 1mg capsule

What to know about Low Dose Naltrexone

How it Works

Low Dose Naltrexone (LDN) refers to dosages of naltrexone that are approximately 10% or more of the typical opioid addiction treatment dosage, typically between 0.5mg to 4.5mg daily. At these lower daily dosages, naltrexone intermittently blocks opioid receptors and exhibits paradoxical properties, including analgesia and anti-inflammatory actions. Studies have shown that it can be beneficial for people with conditions marked by immune system dysfunction.

Who’s it For?

Low-Dose Naltrexone is recommended for individuals with autoimmune conditions, chronic pain, or inflammation. When administered orally, LDN intermittently blocks opioid receptors, which triggers the body to increase the production of endorphins and enkephalins – the body’s natural painkillers and mood elevators.

Effectiveness

Several studies have shown that LDN can be an effective treatment for a range of conditions, including fibromyalgia1 and Crohn’s disease2.

1. American Academy of Pain Medicine, Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study

2. The American Journal of Gastroenterology, Low-Dose Naltrexone Therapy Improves Active Crohn’s Disease

Medical Chart

Low Dose Naltrexone Side Effects

  • Vivid Dreams or Nightmares (first 2 to 3 weeks of therapy)
  • Anxiety
  • Dizziness
  • Constipation

Good to Know

Current studies show that Low Dose Naltrexone is a safe, cost effective and efficacious treatment for chronic pain and autoimmune inflammatory diseases. It is believed that LDN works in the brain by reducing pro-inflammatory chemicals called cytokines, which are known to inflame and sensitize various tissues that can cause pain. By down regulating inflammation in the nervous system, it reduces pain, improves fatigue, sleep, and mood as well as physical function.

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