Clomiphene Citrate

Selective Estrogen Receptor Modulator

At a Glance

  • Oral medication that is taken daily
  • Off-label alternative treatment to standard TRT treatments that help preserve fertility in younger men
  • More convenient treatment option than gels or injections
  • Can take between 14-30 days to see results
  • Available in 25mg and 50mg capsules

The Details

Clomiphene is a Selective Estrogen Receptor Modulator (SERM) used as Testosterone Replacement Therapy for men looking to reduce the effects on their fertility.

Prescription Required
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Starts at $2.30 per 25mg capsule

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What to know about Clomiphene

How it Works

Unlike other Testosterone supplements which increase the amount of testosterone in the body, SERMs like Clomiphene work instead by reducing reactivity to estrogen in the bloodstream which will cause testosterone levels to rise.

Who is it for?

Men of childbearing age with Low-T may choose to go with Clomiphene to avoid the negative effects on fertility and sperm production.


In multiple studies, Clomiphene has been found to be effective in raising testosterone levels without damaging male fertility.1

1. NIH National Library of Medicine, Testosterone versus clomiphene citrate in managing symptoms of hypogonadism in men

Medical Chart

Clomiphene Side Effects

  • Flushing (feelings of warmth)
  • Breast tenderness
  • Weight gain
  • Nausea

Good to know

Clomiphene may be prescribed in addition to other testosterone supplements in order to prevent estrogen levels from rising too high.

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