2-Drug Intracavernosal Injection
At a Glance
- A mixture of two medications
- Must be injected 5 to 15 minutes prior to intercourse
- Available in 4 formulations
- Effectiveness ranges from 1 to 2 hours
- Prescription required
Bimix injections are a combination of two vasodilators, papaverine and phentolamine. Once injected into the cavernosal tissue of the penis, most patients achieve an erection within 5-15 minutes.
Starts at $75 per Vial
What to know about Bimix
How it Works
Bimix is a combination of two vasodilators, papaverine and phentolamine. These two medications when injected directly into the penis can increase the strength and duration of erections.
Who’s it For?
Bimix is a proven and effective treatment option for men who suffer from erectile dysfunction. Bimix injections may also be prescribed in conjunction with other ED treatments.
Bimix works very similarly to other ICI therapies but for men who experience penile pain from Trimix injections, Bimix is a great alternative. Injections are one of the most effective forms of ED treatment: up to 92% of patients find injection therapy effective. According to a 2017 study, Bimix formulations were found to be 94% effective in men with erectile dysfunction.1
1. NIH National Library of Medicine, An Empirical vs Risk-Based Approach Algorithm to Intracavernosal Injection Therapy: A Prospective Study
A common practice, off-label prescribing is when a doctor prescribes a drug for a different condition or at a different dosage than the FDA has approved. For Bimix, there are a few conditions prescribed off-label. Always consult your physician before beginning a new treatment or modifying your existing treatment.
FDA Approved Use
Bimix is often recommended for men suffering from more advanced erectile dysfunction or who have other comorbidities impacting their ED.
Bimix may be prescribed for men who have just had a radical prostatectomy for prostate cancer. Injection Therapy is commonly used to aid in the recovery process.
Bimix Side Effects
- Slight pain at the injection site
- Scarring at injection site (if injections aren’t rotated)
- Priapism (erection lasting more than 4 hours)
Good to Know
Bimix is not typically used more than 3-4 uses during a single week unless directed by your physician.
All vials, whether punctured or sealed, must be refrigerated. Bimix multi-use vials can be used to 28-days after first puncture. Do not freeze.
Level Up Your Knowledge
Can A Healthy Lifestyle Improve Your ED?
In this article Dr. Loh-Doyle explains how four key lifestyle changes can not only improve your erectile function, but will help you maintain your overall good health.
Multi-dose Vials and the 28-day Sterility Rule
In this article Patrick Carpenter, Pharmacist discusses safety guidelines for the use of injectable medicines in multi-dose vials.
The Art of Optimizing Injection Therapy for ED
In this article Dr. Honig discusses why it's important to set the right dose and teach proper self-injection technique in the first office visit.
For instructions and how-to’s, visit our resource center.
Ready to Get Results?
Use these tools to rate and track your progress.
Use this tool to rate your erection. The goal range is 7-9 with 6 being firm enough for penetration.
Log Your Progress
Use the chart below to record your progress. This chart comes in handy when discussing your treatment success with your provider or with a menMD Personal Health Assistant.
Learn more or download the Injection Therapy Guide, which includes these tools, in the resource center.
Ready to get started?
First you’ll need a prescription.
Don’t forget to check these out
Other treatment options for erectile dysfunction.
Vacuum Erection Devices
The VED is a plastic tube that fits over the penis and is pressed against the base of the penis and pubis. It uses suction to pull blood into the penis to create an erection.
Same active ingredient found in Cialis. Taken one hour prior to sexual activity. Effective for up to 36 hours.
Available in 5mg and 20mg tablets or lozenges, prescription required.
Same active ingredient found in Viagra®. Taken orally, 30 to 60 minutes prior to sexual activity.
Available in 20mg and 100mg tablets, prescription required.