menMD can help you connect with a provider
M-F 8am-9pm EST
Sat 9am–5:30pm EST
Selective Estrogen Receptor Modulator
Enclomiphene is a Selective Estrogen Receptor Modulator (SERM) used as Testosterone Replacement Therapy for men with secondary Hypogonadism looking to boost their testosterone while reducing the potential effects on their fertility. Enclomiphene is very similar to Clomiphene but it is a stronger antagonist of the Estrogen receptor than Clomiphene.
Prescription Required
menMD does not compound or dispense prescription products. Prescriptions are filled through our US-licensed pharmacy partners.
Starting at $2.73 per 25mg capsule
Unlike other Testosterone treatments which increase the amount of testosterone in the body, SERMs like Enclomiphene work instead by reducing reactivity to estrogen in the bloodstream which in turn causes testosterone production to increase and testosterone levels to rise.
Enclomiphene is a stronger antagonist of the Estrogen receptor than Clomiphene and this higher affinity for the Estrogen receptor makes it more specific for the receptor, which decreases estrogen-related side effects.
Men of childbearing age with Low-T may choose to use Enclomiphene to avoid the negative effects on fertility, sperm production and testicular size while increasing their testosterone levels.
In multiple studies, Enclomiphene has been found to be effective in raising testosterone levels without damaging male fertility.1, 2. Some studies show a 2x increase in endogenous Testosterone production.
Enclomiphene therapy is not recommended for men with primary hypogonadism, or men who have high levels of circulating gonadotropins (Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH)) with concurrent low testosterone. Enclomiphene monotherapy is also not recommended to be the primary choice of treatment for low testosterone for men that do not require to preserve fertility, as testosterone injections are the most reliable way to alleviate symptomatic low T.
Oral testosterone is finally stepping into the spotlight with new FDA-approved options that deliver consistent results without the mess or needles.
Andropause, often referred to as "male menopause," is a gradual age-related decline in testosterone that affects men's health, mood, and vitality. Understanding its signs and adopting proactive strategies can help maintain quality of life during this natural transition.
This discussion delves into the complexities of low sex drive, exploring potential causes such as erectile dysfunction, medication side effects, and testosterone levels.
Want to Transfer your prescription to menMD? Set up an account and follow the prompts, and we'll do the rest for you!
Transfer My RxOther treatment options for testosterone replacement.
A rapid dissolve tablet, placed between the cheek and gum or on the tongue, taken daily to help boost testosterone levels. Prescription required.
Depo Testosterone Cypionate injections are a safe, effective way to treat hypogonadism or low-T.
Testosterone Pellets are placed under the skin under a local anesthetic and release testosterone consistently into the bloodstream over 4-6 months.
Testosterone topical gels are a simple way to replace testosterone daily without using needles or undergoing an in-office procedure.
menMD Club Membership is your all-access pass to improving your health and wellbeing. Here are some of the many benefits.
Book An Appointment
Book appointments through the menMD Member Portal for 100% confidential treatment support.
The Shop
Find tailored supplements and gear to help enhance your lifestyle in and out of the bedroom.
The Focus
Gain exclusive access to our ongoing webinar series that brings members the best and brightest doctors and men’s health experts to field your anonymous questions on all things guys.
Manage Your Scripts
Keep tabs on your meds and enable AutoFill to give you one less thing to worry about.
Articles
Gain access to our growing library of editorial and video content dedicated to improving all walks of man.
Health Assistant
Connect live with your Personal Health Assistant who can guide you through your health journey.
