What is Peyronie's Disease

Peyronie’s Disease is estimated to affect up to 10% of adult men and is more common as men reach middle age. Although the condition has the biggest impact on sexual intimacy, it has psychological effects as well. Men with PD can experience a loss of confidence, relationship problems, anxiety, and depression.

There are many treatment solutions for Peyronie’s disease including:

Oral Medications

These medications such as generic Pentoxifylline tablets may prevent continued scaring, improve blood circulation, and help reduce the calcification of the plaque. PDE5 Inhibitors are also sometimes prescribed for PD to help with blood flow to the penis.

Topical Creams and Gels

Typically prescribed in combination with injections, these are used between injection sessions on the targeted area.

Injections

Usually patient-specific, injections are intralesional penile injections used to help stabilize the scarring, increase blood flow and reduce deformation. Injections are administered by a trained healthcare provider.

Traction Therapy

Penile Traction Therapy (PTT) involves wearing a traction device to stretch the penis in particular ways to increase penile length and improve curvature. These devices normally require wearing the device daily over a period of 3-6 months to achieve benefits.

Surgery

Surgery is typically considered a second-line treatment for Peyronie’s. Surgical procedures have proven to be effective at a partial resolution of penile curvature. Surgeries typically fall in three categories.

1. Penile Plication – This surgery involves removing or altering the tissue on the side of the penis opposite the plaque to counter the disease’s bending effect.
2. Incision/Excision and Grafting – This surgery involves cutting the scar tissue and placing a graft over the newly created space.
3. Implants – For men with both Peyronie’s Disease and erectile dysfunction who don’t respond to PDE5i oral medications the physician may recommend a penile implant.